Anti-Urokinase 抗体 [U-6] (ab82250)

製品の概要

  • 製品名Anti-Urokinase antibody [U-6]
    Urokinase 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [U-6] to Urokinase
  • 特異性ab82250 binds single and two-chain Urokinase, uPA/PAI-1 complex and uPA/uPAR complex. A reaction is seen with the amino terminal fragment (ATF) but not with LMW Urokinase. ab82250 reacts with reduced and non-reduced Urokinase in Western blotting. It inhibits the enzymatic activity of Urokinase in the fibrin plate assay and can be used on frozen sections in immunohistochemistry applications. ab82250 is specific for human Urokinase. No reaction with human tissue plasminogen activator (tPA) is seen when tested by ELISA, immunoblotting and enzyme inhibition. No reaction with any other human plasma proteins is seen when tested by immunoblotting.
  • アプリケーション適用あり: WB, IHC-Fr, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length native human Urokinase

  • エピトープab82250 binds to the A chain of Urokinase.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab82250 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent concentration. Predicted molecular weight: 49 kDa.
IHC-Fr 1/25.
ELISA Use at an assay dependent concentration.

ターゲット情報

  • 機能Specifically cleave the zymogen plasminogen to form the active enzyme plasmin.
  • 組織特異性Expressed in the prostate gland and prostate cancers.
  • 配列類似性Belongs to the peptidase S1 family.
    Contains 1 EGF-like domain.
    Contains 1 kringle domain.
    Contains 1 peptidase S1 domain.
  • 翻訳後修飾Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ATF antibody
    • ATF uPA antibody
    • BDPLT5 antibody
    • Plasminogen activator antibody
    • Plasminogen activator urinary antibody
    • Plasminogen activator urokinase antibody
    • PLAU antibody
    • QPD antibody
    • u PA antibody
    • U plasminogen activator antibody
    • u-PA antibody
    • U-plasminogen activator antibody
    • uPA antibody
    • URK antibody
    • UROK_HUMAN antibody
    • Urokinase plasminogen activator antibody
    • Urokinase type plasminogen activator antibody
    • Urokinase type plasminogen activator precursor antibody
    • Urokinase-type plasminogen activator chain B antibody
    see all

Anti-Urokinase antibody [U-6] (ab82250) 使用論文

ab82250 has not yet been referenced specifically in any publications.

Product Wall

This antibody ispurified from cell supernatant.


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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"