Anti-Urokinase 抗体 [H77A10] (ab28230)
Key features and details
- Mouse monoclonal [H77A10] to Urokinase
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
製品の概要
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製品名
Anti-Urokinase antibody [H77A10]
Urokinase 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [H77A10] to Urokinase -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse -
免疫原
Recombinant full length protein corresponding to Mouse Urokinase.
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特記事項
This antibody was produced in a knockout mouse.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Avoid freeze / thaw cycle. -
バッファー
pH: 6.60
Constituents: 0.82% Sodium phosphate, 0.87% Sodium chloride -
Concentration information loading...
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精製度
Protein A purified -
一次抗体 備考
This antibody was produced in a knockout mouse. -
ポリ/モノ
モノクローナル -
クローン名
H77A10 -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab28230の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 - 3 µg/ml. Use under non reducing condition. Predicted molecular weight: 48 kDa.
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特記事項 |
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WB
Use a concentration of 1 - 3 µg/ml. Use under non reducing condition. Predicted molecular weight: 48 kDa. |
ターゲット情報
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機能
Specifically cleave the zymogen plasminogen to form the active enzyme plasmin. -
組織特異性
Expressed in the prostate gland and prostate cancers. -
配列類似性
Belongs to the peptidase S1 family.
Contains 1 EGF-like domain.
Contains 1 kringle domain.
Contains 1 peptidase S1 domain. -
翻訳後修飾
Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 18792 Mouse
- SwissProt: P06869 Mouse
- Unigene: 4183 Mouse
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別名
- ATF antibody
- ATF uPA antibody
- BDPLT5 antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (3)
ab28230 は 3 報の論文で使用されています。
- Wu CZ et al. Reduced Expression of Urokinase Plasminogen Activator in Brown Adipose Tissue of Obese Mouse Models. Int J Mol Sci 22:N/A (2021). PubMed: 33810260
- Krause MP et al. Inhibition of plasminogen activator inhibitor-1 restores skeletal muscle regeneration in untreated type 1 diabetic mice. Diabetes 60:1964-72 (2011). WB ; Mouse . PubMed: 21593201
- Khanna A et al. Ets-1 expression and gemcitabine chemoresistance in pancreatic cancer cells. Cell Mol Biol Lett 16:101-13 (2011). WB ; Human . PubMed: 21225469