Anti-Urocortin 3 抗体 (ab77433)
Key features and details
- Goat polyclonal to Urocortin 3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Urocortin 3 antibody
Urocortin 3 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to Urocortin 3 -
由来種
Goat -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide with sequence
KPRQDTAKSPHRTK
, from the internal region of the human protein Urocortin 3 (NP_444277.2) -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, Tris buffered saline -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
ab77433 is purified by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab77433の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 19 kDa (predicted molecular weight: 18 kDa).
A 1 hour primary incubation is recommended for this product. |
特記事項 |
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WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 19 kDa (predicted molecular weight: 18 kDa). A 1 hour primary incubation is recommended for this product. |
ターゲット情報
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関連性
Urocortin 3 is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. A powerful cytoprotective effect of urocortin peptide administration against ischemia and reperfusion injury has been demonstrated in isolated cardiomyocyte models, as well as in the intact heart both in vitro and in vivo. -
細胞内局在
Secreted -
参照データベース
- Entrez Gene: 114131 Human
- Omim: 605901 Human
- SwissProt: Q969E3 Human
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別名
- MGC119002 antibody
- OTTHUMP00000018999 antibody
- Prepro urocortin 3 antibody
see all
画像
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Lanes 1-2 : Anti-Urocortin 3 antibody (ab77433) at 1 µg/ml
Lane 3 : Anti DYKDDDDK-Tag antibody at 1/3000 dilution
Lane 1 : HEK293 cell lysate overexpressing Urocortin 3 with DYKDDDDK tag at 10 µg
Lane 2 : Mock-transfected HEK293 cell
Lane 3 : HEK293 cell lysate overexpressing Urocortin 3 with DYKDDDDK tag at 35 µg
Developed using the ECL technique.
Predicted band size: 18 kDa
Observed band size: 19 kDa why is the actual band size different from the predicted?
データシートおよび資料
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Datasheet download
参考文献 (0)
ab77433 は論文での使用が確認できていません。