製品の概要

  • 製品名URB 597
  • 製品の詳細
    Potent and selective FAAH inhibitor
  • 生理活性の詳細Potent and selective fatty acid amide hydrolase (FAAH) inhibitor (IC50 values are 4.6 nM in brain membranes and 0.5 nM in neurons). Causes accumulation of anandamide. Displays anxiolytic, antidepressant, antinociceptive and analgesic effect.
  • 精製度> 98%
  • 特記事項

    This compound has been found to be unstable in DMSO even at room temperature.

製品の特性

    URB 597 (ab120668) 使用論文

    This product has been referenced in:
    • Hasanein P  et al. URB597, an inhibitor of fatty acid amide hydrolase, reduces hyperalgesia in diabetic rats. Can J Physiol Pharmacol 87:432-9 (2009). Read more (PubMed: 19526037) »
    • Russo R  et al. The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3'-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice. J Pharmacol Exp Ther 322:236-42 (2007). Read more (PubMed: 17412883) »
    • Kathuria S  et al. Modulation of anxiety through blockade of anandamide hydrolysis. Nat Med 9:76-81 (2003). Read more (PubMed: 12461523) »

    See 0 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab120668.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"