1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
機能Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.
組織特異性Predominantly expressed in kidney.
パスウェイPyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from uridine (phosphorylase route): step 1/1.
ab108049, at a 1/50 dilution, staining UPP2 in formalin fixed, paraffin embedded Human kidney carcinoma by Immunohistochemistry, followed by peroxidase conjugation of the secondary antibody and DAB staining.
Anti-UPP2 antibody (ab108049) 使用論文
has not yet been referenced specifically in any publications.