製品の概要

  • 製品名Anti-UNG antibody
    UNG 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to UNG
  • アプリケーション適用あり: IPmore details
    適用なし: WB
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Gorilla
  • 免疫原

    Synthetic peptide corresponding to a region between amino acids 25 and 50 of Human UNG (NP_550433.1).

  • ポジティブ・コントロール
    • Hela whole cell lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: Tris citrate/phosphate, pH 7-8
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab101283 was affinity purified using an epitope specific to UNG immobilized on solid support.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab101283 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP Use at 2-5 µg/mg of lysate.
  • 追加情報Is unsuitable for WB.
  • ターゲット情報

    • 機能Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
    • 組織特異性Isoform 1 is widely expressed with the highest expression in skeletal muscle, heart and testicles. Isoform 2 has the highest expression levels in tissues containing proliferating cells.
    • 関連疾患Defects in UNG are a cause of immunodeficiency with hyper-IgM type 5 syndrome (HIGM5) [MIM:608106]. Hyper-IgM syndrome is a condition characterized by normal or increased serum IgM concentrations associated with low or absent serum IgG, IgA, and IgE concentrations. HIGM5 is associated with profound impairment in immunoglobulin (Ig) class-switch recombination (CSR) at a DNA precleavage step.
    • 配列類似性Belongs to the uracil-DNA glycosylase family.
    • 翻訳後修飾Isoform 1 is processed by cleavage of a transit peptide.
    • 細胞内局在Mitochondrion and Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • DGU antibody
      • DKFZp781L1143 antibody
      • HIGM 4 antibody
      • HIGM4 antibody
      • OTTHUMP00000240527 antibody
      • OTTHUMP00000240528 antibody
      • OTTHUMP00000240529 antibody
      • UDG antibody
      • UNG 1 antibody
      • UNG 15 antibody
      • ung antibody
      • UNG_HUMAN antibody
      • UNG1 antibody
      • UNG15 antibody
      • UNG2 antibody
      • Uracil DNA glycosylase 1 antibody
      • Uracil DNA glycosylase 2 antibody
      • Uracil DNA glycosylase antibody
      • Uracil-DNA glycosylase antibody
      see all

    Anti-UNG antibody 画像

    • anti UNG, at 1 µg/ml, staining UNG in HeLa whole cell lysate immunoprecipitated using ab101283 at 3 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
      Detection: Chemiluminescence with an exposure time of 30 seconds.

    Anti-UNG antibody (ab101283) 使用論文

    ab101283 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab101283.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"