製品の概要

  • 製品名Anti-UNC13C antibody
  • 製品の詳細
    Rabbit polyclonal to UNC13C
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant Protein Epitope Signature Tag antigen: VLDELSVTYG ESFQVIIEEC IKQMSFELNQ MRANGNTTSN KNSAAMDAEI V, corresponding to amino acids 1838 - 1888 of Human UNC13C (Q8NB66).

  • ポジティブ・コントロール
    • Human testis tissue

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーpH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab122725 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Probably plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Probably is involved in neurotransmitter release.
  • 組織特異性Exclusively expressed in brain.
  • 配列類似性Belongs to the unc-13 family.
    Contains 2 C2 domains.
    Contains 1 MHD1 (MUNC13 homology domain 1) domain.
    Contains 1 MHD2 (MUNC13 homology domain 2) domain.
    Contains 1 phorbol-ester/DAG-type zinc finger.
  • ドメインThe C2 domains are not involved in calcium-dependent phospholipid binding.
  • 細胞内局在Cytoplasm. Membrane. Cell junction > synapse > presynaptic cell membrane. Localized to presynaptic structures.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DKFZp547H074 antibody
    • Munc13 3 antibody
    • Munc13-3 antibody
    • Protein unc-13 homolog C antibody
    • UN13C_HUMAN antibody
    • Unc13c antibody
    see all

Anti-UNC13C antibody 画像

  • ab122725, at 1/20 diltuion, staining UNC13C in paraffin-embedded Human testis tissue by Immunohistochemistry.

Anti-UNC13C antibody (ab122725) 使用論文

ab122725 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Western blot
Sample Mouse Tissue lysate - other (whole brain)
Loading amount 100 µg
Specification whole brain
Gel Running Conditions Reduced Denaturing (3.5% stacking gel, 7.5% running gel)
Blocking step Milk as blocking agent for 30 minute(s) · Concentration: 2% · Temperature: 25°C
Username

Abcam user community

Verified customer

投稿 Dec 21 2012

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"