製品の概要

  • 製品名
    UK 14,304 tartrate
  • 製品の詳細
    Selective α2 adrenergic agonist
  • 別名
    • Brimonidine
  • 生理活性の詳細
    Full, selective α2 agonist. Neuroprotective effects.
  • 精製度
    > 99%

製品の特性

参考文献

This product has been referenced in:
  • Lee KY  et al. Brimonidine is neuroprotective against glutamate-induced neurotoxicity, oxidative stress, and hypoxia in purified rat retinal ganglion cells. Mol Vis 16:246-51 (2010). Read more (PubMed: 20161817) »
  • Wang Y  et al. Noradrenergic lesion of the locus coeruleus increases the firing activity of the medial prefrontal cortex pyramidal neurons and the role of alpha2-adrenoceptors in normal and medial forebrain bundle lesioned rats. Brain Res 1324:64-74 (2010). Read more (PubMed: 20153300) »
  • Francis H  et al. The alpha2-adrenergic receptor agonist UK 14,304 inhibits secretin-stimulated ductal secretion by downregulation of the cAMP system in bile duct-ligated rats. Am J Physiol Cell Physiol 293:C1252-62 (2007). Read more (PubMed: 17634418) »
  • Chopin P  et al. Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway. J Pharmacol Exp Ther 288:798-804 (1999). Read more (PubMed: 9918591) »

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