製品の概要

  • 製品名Anti-UHRF1 antibody
    UHRF1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to UHRF1
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    KLH conjugated synthetic peptide selected from the central region of Human UHRF1.

  • ポジティブ・コントロール
    • HeLa cell lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab93419 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報ELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 90 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Putative E3 ubiquitin-protein ligase. May participate in methylation-dependent transcriptional regulation. Binds to inverted 5'-CCAAT-3' box 2 in the TOP2A promoter, and activates TOP2A expression. Important for G1/S transition. May be involved in DNA repair and chromosomal stability.
    • 組織特異性Expressed in thymus, bone marrow, testis, lung and heart. Overexpressed in breast cancer.
    • パスウェイProtein modification; protein ubiquitination.
    • 配列類似性Contains 1 PHD-type zinc finger.
      Contains 2 RING-type zinc fingers.
      Contains 1 ubiquitin-like domain.
      Contains 1 YDG domain.
    • 発生段階Expressed in fetal thymus, liver and kidney.
    • ドメインThe RING finger is required for ubiquitin ligase activity.
      The YDG domain mediates the interaction with histone H3.
    • 翻訳後修飾Phosphorylated on serine residues. Phosphorylation may enhance DNA-binding activity.
      Ubiquitinated; which leads to proteasomal degradation. Polyubiquitination may be stimulated by DNA damage.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Ac2-121 antibody
      • AL022808 antibody
      • E3 ubiquitin-protein ligase UHRF1 antibody
      • EC 6.3.2.- antibody
      • FLJ21925 antibody
      • hNP95 antibody
      • hUHRF1 antibody
      • HuNp95 antibody
      • ICBP90 antibody
      • Inverted CCAAT box binding protein of 90 kDa antibody
      • Inverted CCAAT box binding protein, 90-kD antibody
      • Inverted CCAAT box-binding protein of 90 kDa antibody
      • Liver regeneration-related protein LRRG126 antibody
      • MGC138707 antibody
      • NP95 antibody
      • Nuclear phosphoprotein, 95-KD antibody
      • Nuclear protein 95 antibody
      • Nuclear zinc finger protein Np95 antibody
      • RING finger protein 106 antibody
      • RNF106 antibody
      • Transcription factor ICBP90 antibody
      • Ubiquitin like containing PHD and RING finger domains protein 1 antibody
      • Ubiquitin like PHD and RING finger domain containing protein 1 antibody
      • Ubiquitin-like PHD and RING finger domain-containing protein 1 antibody
      • Ubiquitin-like protein containing PHD and RING finger domains 1 antibody
      • Ubiquitin-like with PHD and ring finger domains 1 antibody
      • Ubiquitin-like, containing PHD and RING finger domains, 1 antibody
      • Ubiquitin-like-containing PHD and RING finger domains protein 1 antibody
      • UHRF1 antibody
      • UHRF1_HUMAN antibody
      see all

    Anti-UHRF1 antibody 画像

    • Anti-UHRF1 antibody (ab93419) at 1/100 dilution + HeLa cell lysate at 35 µg

      Predicted band size : 90 kDa

    Anti-UHRF1 antibody (ab93419) 使用論文

    ab93419 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab93419.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"