Anti-UGT2B15 抗体 (ab89274)
Key features and details
- Mouse polyclonal to UGT2B15
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-UGT2B15 antibody
UGT2B15 一次抗体 製品一覧 -
製品の詳細
Mouse polyclonal to UGT2B15 -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Recombinant full length protein within Human UGT2B15. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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ポジティブ・コントロール
- Human liver lysate, A-431 lysate, UGT2B15 transfected 293T cell lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab89274の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (1) |
Use a concentration of 1 µg/ml. Predicted molecular weight: 61 kDa.
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特記事項 |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 61 kDa. |
ターゲット情報
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機能
UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme displays activity toward several classes of xenobiotic substrates, including simple phenolic compounds, 7-hydroxylated coumarins, flavonoids, anthraquinones, and certain drugs and their hydroxylated metabolites. It also catalyzes the glucuronidation of endogenous estrogens and androgens. -
組織特異性
Expressed in many tissues. Present in liver, prostate and testis. -
配列類似性
Belongs to the UDP-glycosyltransferase family. -
細胞内局在
Microsome membrane. Endoplasmic reticulum membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 7366 Human
- Omim: 600069 Human
- SwissProt: P54855 Human
- Unigene: 150207 Human
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別名
- EC 2.4.1.17 antibody
- HLUG4 antibody
- UDB15_HUMAN antibody
see all
画像
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Anti-UGT2B15 antibody (ab89274) at 1 µg/ml + Human liver lysate at 50 µg
Developed using the ECL technique.
Predicted band size: 61 kDa
Observed band size: 55 kDa why is the actual band size different from the predicted? -
Anti-UGT2B15 antibody (ab89274) at 1 µg/ml + A-431 cell lysate at 50 µg
Developed using the ECL technique.
Predicted band size: 61 kDa
Observed band size: 50 kDa why is the actual band size different from the predicted? -
All lanes : Anti-UGT2B15 antibody (ab89274) at 1 µg/ml
Lane 1 : UGT2B15 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Developed using the ECL technique.
Predicted band size: 61 kDa
Observed band size: 61 kDa
データシートおよび資料
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Datasheet download
参考文献 (3)
ab89274 は 3 報の論文で使用されています。
- Hertzog JR et al. AKR1C3 mediates pan-AR antagonist resistance in castration-resistant prostate cancer. Prostate 80:1223-1232 (2020). PubMed: 33258507
- Obst JK et al. Revealing Metabolic Liabilities of Ralaniten To Enhance Novel Androgen Receptor Targeted Therapies. ACS Pharmacol Transl Sci 2:453-467 (2019). PubMed: 32259077
- Grant DJ et al. UDP-glucuronosyltransferases and biochemical recurrence in prostate cancer progression. BMC Cancer 17:463 (2017). IHC-P ; Human . PubMed: 28673330