製品の概要

  • 製品名Anti-UGGT antibody [EPR5105]
    UGGT 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR5105] to UGGT
  • アプリケーション適用あり: WB, IHC-Pmore details
    適用なし: Flow Cyt,ICC or IP
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to residues in Human UGGT (Q9NYU2).

  • ポジティブ・コントロール
    • Human skeletal muscle, BXPC-3, SH-SY5Y, and MCF7 lysates, Human brain tissue
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 精製度Tissue culture supernatant
  • ポリ/モノモノクローナル
  • クローン名EPR5105
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab124879 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/10000 - 1/50000. Detects a band of approximately 170 kDa (predicted molecular weight: 177 kDa).
IHC-P 1/100 - 1/250.
  • 追加情報Is unsuitable for Flow Cyt,ICC or IP.
  • ターゲット情報

    • 機能Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
    • 組織特異性Higher levels in pancreas, skeletal muscle, kidney, and brain. Low levels in lung and heart.
    • パスウェイProtein modification; protein glycosylation.
    • 配列類似性Belongs to the glycosyltransferase 8 family.
    • ドメインThe N-terminal non-catalytic domain is assumed to mediate recognition of proteins with partial folding defects.
    • 細胞内局在Endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment.
    • Information by UniProt
    • 参照データベース
    • 別名
      • GT antibody
      • HUGT1 antibody
      • UDP glucose glycoprotein glucosyltransferase 1 antibody
      • UDP Glucose Glycoprotein Glucosyltransferase antibody
      • UDP--Glc:glycoprotein glucosyltransferase antibody
      • UDP-glucose ceramide glucosyltransferase-like 1 antibody
      • UDP-glucose:glycoprotein glucosyltransferase 1 antibody
      • UGCGL1 antibody
      • UGGG1 antibody
      • UGGG1_HUMAN antibody
      • UGGT antibody
      • Uggt1 antibody
      • UGT1 antibody
      • UGTR antibody
      see all

    Anti-UGGT antibody [EPR5105] 画像

    • All lanes : Anti-UGGT antibody [EPR5105] (ab124879) at 1/10000 dilution

      Lane 1 : Human skeletal muscle lysate
      Lane 2 : BXPC-3 cell lysate
      Lane 3 : SH-SY5Y cell lysate
      Lane 4 : MCF7 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 177 kDa
    • Staining of UGGT in Paraffin-embedded Human brain tissue by Immunohistochemistry using ab124879 at a dilution of 1/100.

    Anti-UGGT antibody [EPR5105] (ab124879) 使用論文

    ab124879 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab124879.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"