製品の概要

  • 製品名
    UDP-glucose
  • 製品の詳細
    Highly potent P2Y14 agonist
  • 別名
    • UDP-glc
    • Uridine 5'-diphosphoglucose
    • Uridine-diphosphate-glucose disodium salt
  • 生理活性の詳細
    Highly potent, endogenous P2Y14 agonist (EC50 = 82 nM). Involved in modulation of gastric function. UDP also available (ab120383).

製品の特性

  • 体系名
    Uridine 5'-diphosphoglucose disodium salt
  • 分子量
    610.27
  • 構造式
    Chemical Structure
  • 分子式
    C15H22N2Na2O17P2
  • CAS 番号
    28053-08-9
  • 保存方法
    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • 溶解性
    Soluble in water to 100 mM
  • 使用に関する注意

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES 線形表記
    O=C1C=CN(C(=O)N1)[C@@H]3O[C@H](COP(=O)(OP(=O)(O[C@@H]2OC(CO)[C@@H](O)[C@@H](O)[C@@H]2O)O[Na])O[Na])[C@@H](O)[C@H]3O
  • 由来

    Synthetic

  • 研究分野

参考文献

This product has been referenced in:
  • Bassil AK  et al. UDP-glucose modulates gastric function through P2Y14 receptor-dependent and -independent mechanisms. Am J Physiol Gastrointest Liver Physiol 296:G923-30 (2009). Read more (PubMed: 19164486) »
  • Fricks IP  et al. Gi-dependent cell signaling responses of the human P2Y14 receptor in model cell systems. J Pharmacol Exp Ther 330:162-8 (2009). Read more (PubMed: 19339661) »
  • Abbracchio MP  et al. Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family. Trends Pharmacol Sci 24:52-5 (2003). Read more (PubMed: 12559763) »

See 0 Publications for this product

レビューと Q&A

Thank you for contacting us. I have heard back from the lab with the following information: "We can confirm that the UDP-glucose does contain small amounts of UDP as it is used in the synthesis of this compound. Based on the HPLC the level of UDP is ap...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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