製品の概要

  • 製品名UCPH-101
  • 製品の詳細
    Selective EAAT1 inhibitor
  • 生理活性の詳細Selective inhibitor of EAAT1 (IC50 = 0.67 μM). Displays >400-fold selectivity over EAAT2 and EAAT3.

    Blood-brain barrier permeable analog UCPH-102 also available (ab146404).
  • 精製度> 98%

法規制情報

製品の特性

    UCPH-101 (ab120309) 使用論文

    This product has been referenced in:
    • Erichsen MN  et al. Structure-activity relationship study of first selective inhibitor of excitatory amino acid transporter subtype 1: 2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101). J Med Chem 53:7180-91 (2010). Read more (PubMed: 20857912) »
    • Jensen AA  et al. Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1. J Med Chem 52:912-5 (2009). Read more (PubMed: 19161278) »

    See all 3 Publications for this product

    Product Wall

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