製品の概要

  • 製品名Anti-UCHL3 antibody
    UCHL3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to UCHL3
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rat
  • 免疫原

    Synthetic peptide from an internal sequence of Human UCHL3, conjugated to KLH.

  • ポジティブ・コントロール
    • Human testis tissue.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab62035 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 10 µg/ml.

ターゲット情報

  • 機能Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. Has a 10-fold preference for Arg and Lys at position P3". Deubiquitinates ENAC in apical compartments, thereby regulating apical membrane recycling. Indirectly increases the phosphorylation of IGFIR, AKT and FOXO1 and promotes insulin-signaling and insulin-induced adipogenesis. Required for stress-response retinal, skeletal muscle and germ cell maintenance. May be involved in working memory.
  • 組織特異性Highly expressed in heart, skeletal muscle, and testis.
  • 配列類似性Belongs to the peptidase C12 family.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Ubiquitin carboxyl-terminal hydrolase isozyme L3 antibody
    • Ubiquitin thioesterase L3 antibody
    • Ubiquitin thiolesterase antibody
    • Ubiquitin thiolesterase L3 antibody
    • UCH L3 antibody
    • UCH-L3 antibody
    • UCHL3 antibody
    • UCHL3_HUMAN antibody
    see all

Anti-UCHL3 antibody 画像

  • ab62035 at 10µg/ml staining UCHL3 in human testis by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.

Anti-UCHL3 antibody (ab62035) 使用論文

ab62035 has not yet been referenced specifically in any publications.

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