製品の概要

  • 製品名Anti-UCHL3 antibody
    UCHL3 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to UCHL3
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: PEERARYLEN YDAIRVTHET SAHEGQTEAP SIDEKVDLHF IALVHVDGHL YELDGRKPFP INHGETSDET LLEDAIEVCK KFMERDPDEL RFNAIALSAA , corresponding to amino acids 131-231 of Human UCHL3

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab57689 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. Has a 10-fold preference for Arg and Lys at position P3". Deubiquitinates ENAC in apical compartments, thereby regulating apical membrane recycling. Indirectly increases the phosphorylation of IGFIR, AKT and FOXO1 and promotes insulin-signaling and insulin-induced adipogenesis. Required for stress-response retinal, skeletal muscle and germ cell maintenance. May be involved in working memory.
    • 組織特異性Highly expressed in heart, skeletal muscle, and testis.
    • 配列類似性Belongs to the peptidase C12 family.
    • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 細胞内局在Cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Ubiquitin carboxyl-terminal hydrolase isozyme L3 antibody
      • Ubiquitin thioesterase L3 antibody
      • Ubiquitin thiolesterase antibody
      • Ubiquitin thiolesterase L3 antibody
      • UCH L3 antibody
      • UCH-L3 antibody
      • UCHL3 antibody
      • UCHL3_HUMAN antibody
      see all

    Anti-UCHL3 antibody 画像



    • Predicted band size : 26 kDa
      UCHL3 antibody (ab57689) at 1ug/lane + K-562 cell lysate at 25ug/lane.

    Anti-UCHL3 antibody (ab57689) 使用論文

    This product has been referenced in:
    • Trott D  et al. Effect of phosphorylated hsp27 on proliferation of human endothelial and smooth muscle cells. Proteomics 9:3383-94 (2009). Read more (PubMed: 19562804) »

    See 1 Publication for this product

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    There are currently no Abreviews or Questions for ab57689.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"