製品の概要

  • 製品名
    Anti-UBXN6 antibody [2F8-24]
    UBXN6 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [2F8-24] to UBXN6
  • 特異性
    Only detects the full-length isoform.
  • アプリケーション
    適用あり: WB, IP, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length Human protein

  • ポジティブ・コントロール
    • U20S cell lysate

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, 0.5% PBS, 0.1% BSA
  • Concentration information loading...
  • 精製度
    Protein A purified
  • ポリ/モノ
    モノクローナル
  • クローン名
    2F8-24
  • アイソタイプ
    IgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab81555 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 50 kDa.
IP Use at 1-2 - 0.5 µg/mg of lysate.
ICC/IF Use a concentration of 0.05 - 0.5 µg/ml.

ターゲット情報

  • 機能
    Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. MDM2 stabilization leads to MDM2-dependent TP53 degradation.
  • 組織特異性
    Enhanced expression in testis.
  • 配列類似性
    Contains 1 PUB (PUG) domain.
    Contains 1 UBX domain.
  • ドメイン
    The UBX domain lacks key residues critical for VCP binding.
  • 細胞内局在
    Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Localizes at the centrosome both in interphase and during mitosis.
  • Information by UniProt
  • 参照データベース
  • 別名
    • UBX domain containing 1 antibody
    • UBX domain containing 2 antibody
    • UBX domain containing protein 1 antibody
    • UBX domain containing protein 6 antibody
    • UBX domain protein 6 antibody
    • UBX domain-containing protein 1 antibody
    • UBX domain-containing protein 6 antibody
    • UBXD1 antibody
    • UBXDC2 antibody
    • Ubxn6 antibody
    • UBXN6_HUMAN antibody
    see all

画像

  • All lanes : Anti-UBXN6 antibody [2F8-24] (ab81555) at 1 µg/ml

    Lane 1 : U20S cells transfected with UBXN6 shRNA
    Lane 2 : U20S cells transfected with mismatch control shRNA


    Predicted band size : 50 kDa
    Observed band size : 54 kDa (why is the actual band size different from the predicted?)

参考文献

ab81555 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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