製品の概要

  • 製品名Anti-UBE4B antibody
    UBE4B 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to UBE4B
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: FKLLAEKVEE IVAKNARAEI DYSDAPDEFR DPLMDTLMTD PVRLPSGTIM DRSIILRHLL NSPTDPFNRQ TLTESMLEPV PELKEQIQAW MREKQNSDH, corresponding to amino acids 1075-1174 of Human UBE4B

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab56691 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3.
    • 組織特異性Highest expression in ovary, testis, heart and skeletal muscle. Expression is low in colon, thymus and peripheral blood leukocytes. Almost undetectable in lung and spleen.
    • 配列類似性Belongs to the ubiquitin conjugation factor E4 family.
      Contains 1 U-box domain.
    • 翻訳後修飾Proteolytically cleaved by caspases during apoptosis. Cleaved efficiently at Asp-123 by caspase-6 and granzyme B. Cleaved with approximately 10-fold less efficiency at Asp-109 by caspase-3 and caspase-7.
    • 細胞内局在Cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 4930551I19Rik antibody
      • 4933406G05Rik antibody
      • AU014668 antibody
      • D4Bwg0973e antibody
      • E4 antibody
      • HDNB1 antibody
      • Homozygously deleted in neuroblastoma 1 antibody
      • KIAA0684 antibody
      • mKIAA0684 antibody
      • RP23 173D8.1 antibody
      • Ube4b antibody
      • UBE4B_HUMAN antibody
      • Ubiquitin conjugation factor E4 B antibody
      • Ubiquitin fusion degradation protein 2 antibody
      • UBOX3 antibody
      • UFD2 antibody
      • UFD2a antibody
      • Ufd2p antibody
      see all

    Anti-UBE4B antibody 画像



    • Predicted band size : 146 kDa

    Anti-UBE4B antibody (ab56691) 使用論文

    ab56691 has not yet been referenced specifically in any publications.

    Product Wall

    Abcam has not validated the combination of species/application used in this Abreview.
    Application Immunocytochemistry/ Immunofluorescence
    Sample Human Cell (U2OS)
    Specification U2OS
    Fixative Paraformaldehyde
    Permeabilization No
    Blocking step BSA as blocking agent for 30 minute(s) · Concentration: 10% · Temperature: RT°C
    Username

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    投稿 Mar 25 2011

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"