製品の概要

  • 製品名Anti-Ube2B antibody
    Ube2B 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to Ube2B
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full-length Human Ube2B protein (AAH08470.1)

  • ポジティブ・コントロール
    • Ube2B transfected 293T lysate and Jurkat cell lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab92919 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: 1/500 - 1/1000. Predicted molecular weight: 17 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'- and 'Lys-63'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA. Associates to the E3 ligase RAD18 to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. May be involved in neurite outgrowth.
    • パスウェイProtein modification; protein ubiquitination.
    • 配列類似性Belongs to the ubiquitin-conjugating enzyme family.
    • 細胞内局在Cell membrane. Nucleus. In peripheral neurons, expressed both at the plasma membrane and in nuclei.
    • Information by UniProt
    • 参照データベース
    • 別名
      • E2 17kDa antibody
      • E2 protein antibody
      • hHR6B antibody
      • HR6B antibody
      • RAD6 homolog B antibody
      • RAD6B antibody
      • UBC2 antibody
      • UBE2B antibody
      • UBE2B_HUMAN antibody
      • Ubiquitin carrier protein B antibody
      • Ubiquitin conjugating enzyme E2 B antibody
      • Ubiquitin conjugating enzyme E2B (RAD6 homolog) antibody
      • Ubiquitin conjugating enzyme E2B antibody
      • Ubiquitin protein ligase B antibody
      • Ubiquitin-conjugating enzyme E2 17 kDa antibody
      • Ubiquitin-conjugating enzyme E2 B antibody
      • Ubiquitin-conjugating enzyme E2-17 kDa antibody
      • Ubiquitin-protein ligase B antibody
      see all

    Anti-Ube2B antibody 画像

    • Anti-Ube2B antibody (ab92919) at 500 µg + Jurkat cell lysate at 50 µg

      Predicted band size : 17 kDa
    • All lanes : Anti-Ube2B antibody (ab92919) at 1/500 dilution

      Lane 1 : Ube2B transfected 293T lysate
      Lane 2 : Non-transfected 293T lysate

      Lysates/proteins at 25 µg per lane.


      Predicted band size : 17 kDa
      Observed band size : 17 kDa

    Anti-Ube2B antibody (ab92919) 使用論文

    ab92919 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab92919.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"