製品の概要

  • 製品名Anti-UBE1C antibody [MILR42872]
    UBE1C 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [MILR42872] to UBE1C
  • アプリケーション適用あり: WBmore details
    適用なし: Flow Cyt,ICC/IF,IHC-P or IP
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    A synthetic peptide corresponding to residues in human UBE1C

  • ポジティブ・コントロール
    • Lysates of: fetal lung, 293T, HeLa, RAW 264.7, HepG2, K562
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

     

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • バッファーPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 精製度Tissue culture supernatant
  • ポリ/モノモノクローナル
  • クローン名MILR42872
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab124728 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/10000 - 1/50000. Predicted molecular weight: 49 kDa.
  • 追加情報Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • ターゲット情報

    • 機能Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression.
    • 組織特異性Ubiquitously expressed.
    • パスウェイProtein modification; protein neddylation.
    • 配列類似性Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
    • Information by UniProt
    • 参照データベース
    • 別名
      • DKFZp566J164 antibody
      • EC 6.3.2. antibody
      • hUba3 antibody
      • MGC22384 antibody
      • NEDD8 activating enzyme E1 catalytic subunit antibody
      • NEDD8 activating enzyme E1C antibody
      • Nedd8 activating enzyme hUba3 antibody
      • NEDD8-activating enzyme E1 catalytic subunit antibody
      • NEDD8-activating enzyme E1C antibody
      • uba3 antibody
      • UBA3 ubiquitin activating enzyme E1 homolog antibody
      • UBA3_HUMAN antibody
      • UBE1C antibody
      • Ubiquitin activating enzyme 3 antibody
      • Ubiquitin activating enzyme E1C antibody
      • Ubiquitin-activating enzyme 3 antibody
      • Ubiquitin-activating enzyme E1C antibody
      • Ubiquitin-like modifier-activating enzyme 3 antibody
      see all

    Anti-UBE1C antibody [MILR42872] 画像

    • All lanes : Anti-UBE1C antibody [MILR42872] (ab124728)

      Lane 1 : Fetal lung cell lysate
      Lane 2 : 293T cell lysate
      Lane 3 : HeLa cell lysate
      Lane 4 : RAW 264.7 cell lysate
      Lane 5 : HepG2 cell lysate
      Lane 6 : K562 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 49 kDa

    Anti-UBE1C antibody [MILR42872] (ab124728) 使用論文

    ab124728 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab124728.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"