製品の概要

  • 製品名Anti-UACA antibody
    UACA 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to UACA
  • アプリケーション適用あり: IP, IHC-Pmore details
    適用なし: WB
  • 種交差性
    交差種: Human
    交差が予測される動物種: Cow, Chimpanzee
  • 免疫原

    Synthetic peptide corresponding to a region between residue 675-725 (KAKLAQHVKP EEHEQVKSRL EQKSGELGKK ITELTLKNQT LQKEIEKVYL D) of Human UACA (NP_060473.2).

  • ポジティブ・コントロール
    • HeLa whole cell lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: Tris citrate/phosphate buffer, pH 7-8
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab99321 was affinity purified using an epitope specific to UACA immobilized on solid support.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab99321 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP Use at 2-5 µg/mg of lysate.
IHC-P Use at an assay dependent concentration.
  • 追加情報Is unsuitable for WB.
  • ターゲット情報

    • 機能Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1.
      Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury.
    • 組織特異性Highly expressed in skeletal muscle, heart, kidney and pancreas. Expressed in choroid, retina and epidermal melanocytes. Expressed in eye muscles and thyroid follicular cells.
    • 配列類似性Contains 6 ANK repeats.
    • 細胞内局在Nucleus. Cytoplasm. Cytoplasm > cytoskeleton. Expressed diffusely in cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • FLJ10128 antibody
      • KIAA1561 antibody
      • MGC141967 antibody
      • MGC141969 antibody
      • Nuclear membrane binding protein antibody
      • NUCLING antibody
      • UACA antibody
      • UACA_HUMAN antibody
      • Uveal autoantigen with coiled coil domains and ankyrin repeats antibody
      • Uveal autoantigen with coiled-coil domains and ankyrin repeats antibody
      see all

    Anti-UACA antibody 画像

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human prostate carcinoma tissue labelling UACA with ab99321 at 1/1000 (1µg/ml). Detection: DAB.
    • Detection of UACA in Immunoprecipitates of HeLa whole cell lysate (1 mg for IP, 20% of IP loaded) using ab99321 at 3 µg/mg lysate for IP. ab99323, at 1 µg/ml, was used for subsequent Western blot detection. Detection: Chemiluminescence with an exposure time of 3 seconds.

    Anti-UACA antibody (ab99321) 使用論文

    ab99321 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab99321.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"