Anti-Two pore calcium channel protein 2 抗体 (ab119915)


  • 製品名Anti-Two pore calcium channel protein 2 antibody
    Two pore calcium channel protein 2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Two pore calcium channel protein 2
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide from the N-terminus of Human Two pore calcium channel protein 2 (NM_139075.3).

  • ポジティブ・コントロール
    • MCF7 cell lysate, Human fetal small intestine tissue.


  • 製品の状態Lyophilised:Reconstitute with 200ul distilled sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary.
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーpH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 99% PBS, 0.5% BSA
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab119915 is purified by a peptide affinity column.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野



Our Abpromise guarantee covers the use of ab119915 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 98 kDa (predicted molecular weight: 85 kDa).
IHC-P 1/100 - 1/500.


  • 機能Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca(2+) channels (VDCC) across the lysosomal membrane. May be involved in smooth muscle contraction.
  • 組織特異性Widely expressed. Expressed at high level in liver and kidney.
  • 配列類似性Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. Two pore calcium channel subfamily.
  • ドメインEach of the two internal repeats contains five hydrophobic transmembrane segments (S1, S2, S3, S5, S6) and one positively charged transmembrane segment (S4). S4 segments probably represent the voltage-sensor and are characterized by a series of positively charged amino acids at every third position.
  • 翻訳後修飾N-glycosylated.
  • 細胞内局在Lysosome membrane. Only the acidic lysosomal fraction is sensitive to NAADP.
  • Information by UniProt
  • 参照データベース
  • 別名
    • SHEP10 antibody
    • TPC2 antibody
    • TPC2_HUMAN antibody
    • tpcn2 antibody
    • Two pore calcium channel protein 2 antibody
    • two pore segment channel 2 antibody
    • Two-pore channel 2 antibody
    • Voltage dependent calcium channel protein TPC2 antibody
    • Voltage-dependent calcium channel protein TPC2 antibody
    see all

Anti-Two pore calcium channel protein 2 antibody 画像

  • Anti-Two pore calcium channel protein 2 antibody (ab119915) at 1/500 dilution + MCF7 cell lysate

    Predicted band size : 85 kDa

    The amount of protein per lane: 30ug

    PVDF membrane

    Blocking solution: 5% (W/V) skim milk, with 1 X TBST buffer

    Shake membrane at room temperature with ab119915, 1/500, for 30 minutes, then transfer to 4°C overnight.
  • ab119915 at 1/100 dilution staining Two pore calcium channel protein 2 in Formalin-fixed, Paraffin-embedded Human fetal small intestine tissue by Immunohistochemistry.

Anti-Two pore calcium channel protein 2 antibody (ab119915) 使用論文

ab119915 has not yet been referenced specifically in any publications.

Product Wall

Thank you for confirming these details and for your cooperation. The details provided enable us to closely monitor the quality of our products.

I am sorry this product did not perform as stated on the datasheet and for the inconvenience this...

Read More

Thank you for taking the time to provide this information. The details you have kindly provided will provide us with vital information for our monitoring of product quality

I appreciate the time you have spent in the laboratory and understan...

Read More

Thank you for your reply and for kindly providing the image again which I have been able to access.

I see there is one clear single band in the sample lane on the blot. Because of the image quality, and because some of the bands are very fai...

Read More

Thank you for taking the time to contact us. I am sorry to hear you have had difficulty obtaining satisfactory results from this antibody.

I would like to reassure you that this antibody is tested and covered by our 6 month guarantee for WB ...

Read More