Anti-Two pore calcium channel protein 2 抗体 (ab111145)

製品の概要

  • 製品名Anti-Two pore calcium channel protein 2 antibody
    Two pore calcium channel protein 2 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Two pore calcium channel protein 2
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH corresponding to a region within the C Terminal of Human Two pore calcium channel protein 2.

  • ポジティブ・コントロール
    • Human colon and pancreas tissue

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーpH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab111145 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca(2+) channels (VDCC) across the lysosomal membrane. May be involved in smooth muscle contraction.
  • 組織特異性Widely expressed. Expressed at high level in liver and kidney.
  • 配列類似性Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. Two pore calcium channel subfamily.
  • ドメインEach of the two internal repeats contains five hydrophobic transmembrane segments (S1, S2, S3, S5, S6) and one positively charged transmembrane segment (S4). S4 segments probably represent the voltage-sensor and are characterized by a series of positively charged amino acids at every third position.
  • 翻訳後修飾N-glycosylated.
  • 細胞内局在Lysosome membrane. Only the acidic lysosomal fraction is sensitive to NAADP.
  • Information by UniProt
  • 参照データベース
  • 別名
    • SHEP10 antibody
    • TPC2 antibody
    • TPC2_HUMAN antibody
    • tpcn2 antibody
    • Two pore calcium channel protein 2 antibody
    • two pore segment channel 2 antibody
    • Two-pore channel 2 antibody
    • Voltage dependent calcium channel protein TPC2 antibody
    • Voltage-dependent calcium channel protein TPC2 antibody
    see all

Anti-Two pore calcium channel protein 2 antibody 画像

  • ab111145, at 3.75 µg/ml, staining Two pore calcium channel protein 2 in formalin fixed, paraffin embedded Human colon tissue by Immunohistochemistry. Followed by biotinylated secondary antibody, alkaline phosphatase streptavidin and chromogen.
  • ab111145, at 3.75 µg/ml, staining Two pore calcium channel protein 2 in formalin fixed, paraffin embedded Human pancreas tissue by Immunohistochemistry. Followed by biotinylated secondary antibody, alkaline phosphatase streptavidin and chromogen.

Anti-Two pore calcium channel protein 2 antibody (ab111145) 使用論文

ab111145 has not yet been referenced specifically in any publications.

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