製品の概要

  • 製品名
    Anti-TWEAK antibody (Biotin)
    TWEAK 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to TWEAK (Biotin)
  • 標識
    Biotin
  • アプリケーション
    適用あり: ELISA, Sandwich ELISA, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Highly pure (>98%) recombinant human TWEAK.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab83437 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
Sandwich ELISA
WB
  • 追加情報
    ELISA: Use at a concentration of 0.25 - 1 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant human TWEAK.
    sELISA: Use at a concentration of 0.25 - 1 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant human TWEAK.
    WB: Use at a concentration of 0.1 - 0.2 µg/ml. The detection limit for recombinant human TWEAK is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions. Predicted molecular weight: 27 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines.
    • 組織特異性
      Highly expressed in adult heart, pancreas, skeletal muscle, brain, colon, small intestine, lung, ovary, prostate, spleen, lymph node, appendix and peripheral blood lymphocytes. Low expression in kidney, testis, liver, placenta, thymus and bone marrow. Also detected in fetal kidney, liver, lung and brain.
    • 配列類似性
      Belongs to the tumor necrosis factor family.
    • 翻訳後修飾
      The soluble form derives from the membrane form by proteolytic processing.
    • 細胞内局在
      Secreted and Cell membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • APO 3 ligand antibody
      • APO 3L antibody
      • APO3 ligand antibody
      • APO3/DR3 ligand antibody
      • APO3L antibody
      • DR3LG antibody
      • MGC129581 antibody
      • MGC20669 antibody
      • secreted form antibody
      • TNF-related weak inducer of apoptosis antibody
      • TNF12_HUMAN antibody
      • TNFSF 12 antibody
      • Tnfsf12 antibody
      • TNFSF12 protein antibody
      • Tumor necrosis factor (ligand) superfamily member 12 antibody
      • Tumor necrosis factor ligand superfamily member 12 antibody
      • Tumor necrosis factor superfamily member 12 antibody
      • TWEAK antibody
      • UNQ181/PRO207 antibody
      see all

    プロトコール

    参考文献

    ab83437 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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