製品の概要

  • 製品名Anti-TWEAK antibody
    TWEAK 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to TWEAK
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: SLSAQEPAQE ELVAEEDQDP SELNPQTEES QDPAPFLNRL VRPRRSAPKG RKTRARRAIA AHYEVHPRPG QDGAQADGGY TTCLRP, corresponding to amino acids 49-135 of Human TWEAK

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab57926 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines.
    • 組織特異性Highly expressed in adult heart, pancreas, skeletal muscle, brain, colon, small intestine, lung, ovary, prostate, spleen, lymph node, appendix and peripheral blood lymphocytes. Low expression in kidney, testis, liver, placenta, thymus and bone marrow. Also detected in fetal kidney, liver, lung and brain.
    • 配列類似性Belongs to the tumor necrosis factor family.
    • 翻訳後修飾The soluble form derives from the membrane form by proteolytic processing.
    • 細胞内局在Secreted and Cell membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • APO 3 ligand antibody
      • APO 3L antibody
      • APO3 ligand antibody
      • APO3/DR3 ligand antibody
      • APO3L antibody
      • DR3LG antibody
      • MGC129581 antibody
      • MGC20669 antibody
      • secreted form antibody
      • TNF-related weak inducer of apoptosis antibody
      • TNF12_HUMAN antibody
      • TNFSF 12 antibody
      • Tnfsf12 antibody
      • TNFSF12 protein antibody
      • Tumor necrosis factor (ligand) superfamily member 12 antibody
      • Tumor necrosis factor ligand superfamily member 12 antibody
      • Tumor necrosis factor superfamily member 12 antibody
      • TWEAK antibody
      • UNQ181/PRO207 antibody
      see all

    Anti-TWEAK antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab57926 TWEAK antibody at 1ug/ml. Predicted band size of immunogen is 33 kDa

    Anti-TWEAK antibody (ab57926) 使用論文

    ab57926 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab57926.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"