製品の概要

  • 製品名Anti-TUBB8 antibody
    TUBB8 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TUBB8
  • アプリケーション適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rat, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within amino acids 366 and 430 of Human TUBB8 (NP_817124).

  • ポジティブ・コントロール
    • 293T, A431, H1299, HeLaS3, HepG2, MOLT4 and Raji cell lines

法規制情報

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab97880 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 50 kDa.
ICC/IF 1/100 - 1/200.

ターゲット情報

  • 機能Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
  • 配列類似性Belongs to the tubulin family.
  • 翻訳後修飾Some glutamate residues at the C-terminus are polyglutamylated. This modification occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Also monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human. Monoglycylation is mainly limited to tubulin incorporated into axonemes (cilia and flagella) whereas glutamylation is prevalent in neuronal cells, centrioles, axonemes, and the mitotic spindle. Both modifications can coexist on the same protein on adjacent residues, and lowering glycylation levels increases polyglutamylation, and reciprocally. The precise function of such modifications is still unclear but they regulate the assembly and dynamics of axonemal microtubules.
  • 細胞内局在Cytoplasm > cytoskeleton.
  • Information by UniProt
  • 参照データベース
  • 別名
    • bA631M21.2 antibody
    • Class VIII beta tubulin antibody
    • HSA10p15 beta tubulin 4Q antibody
    • RP11-631M21.2 antibody
    • TBB8_HUMAN antibody
    • TUBB8 antibody
    • Tubulin beta 8 antibody
    • Tubulin beta 8 chain antibody
    • Tubulin beta 8 class VIII antibody
    • Tubulin beta-8 chain antibody
    see all

Anti-TUBB8 antibody 画像

  • All lanes : Anti-TUBB8 antibody (ab97880) at 1/1000 dilution

    Lane 1 : A431 whole cell lysate
    Lane 2 : H1299 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 50 kDa
  • Immunofluorescence analysis of TUBB8 in paraformaldehyde fixed HeLa, using ab97880 at a 1/200 dilution.
    Lower image: merged with DNA probe.

Anti-TUBB8 antibody (ab97880) 使用論文

ab97880 has not yet been referenced specifically in any publications.

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