製品の概要

  • 製品名Anti-TUBB2A antibody
    TUBB2A 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TUBB2A
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 409-438 of Human TUBB2A (NP_001060.1).

  • ポジティブ・コントロール
    • 293 cell line lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab116372 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 50 kDa.

ターゲット情報

  • 機能Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
  • 配列類似性Belongs to the tubulin family.
  • 翻訳後修飾Some glutamate residues at the C-terminus are polyglutamylated. This modification occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Also monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human. Monoglycylation is mainly limited to tubulin incorporated into axonemes (cilia and flagella) whereas glutamylation is prevalent in neuronal cells, centrioles, axonemes, and the mitotic spindle. Both modifications can coexist on the same protein on adjacent residues, and lowering glycylation levels increases polyglutamylation, and reciprocally. The precise function of such modifications is still unclear but they regulate the assembly and dynamics of axonemal microtubules.
  • 細胞内局在Cytoplasm > cytoskeleton.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Class IIa beta tubulin antibody
    • dJ40E16.7 antibody
    • M(beta)2 antibody
    • TBB2A_HUMAN antibody
    • TUBB antibody
    • TUBB2 antibody
    • Tubb2a antibody
    • Tubulin beta 2 antibody
    • Tubulin beta 2A antibody
    • Tubulin beta 2A class IIa antibody
    • Tubulin beta polypeptide 2 antibody
    • Tubulin beta polypeptide antibody
    • Tubulin beta-2A chain antibody
    see all

Anti-TUBB2A antibody 画像

  • Anti-TUBB2A antibody (ab116372) at 1/100 dilution + 293 cell line lysate at 35 µg

    Predicted band size : 50 kDa

Anti-TUBB2A antibody (ab116372) 使用論文

ab116372 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"