製品の概要

  • 製品名Anti-TSPYL1 antibody
    TSPYL1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to TSPYL1
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Recombinant Fragment
    交差が予測される動物種: Human
  • 免疫原

    Recombinant fragment: MSGLDGVKRT TPLQTHSIII SDQVPSDQDA HQYLRLRDQS EATQVMAEPG EGGSETVALP PPPPSEEGGV PQDAAGRGGT PQIRVVGGRG HVAIKAGQEE , corresponding to amino acids 1-101 of Human TSPYL1 with a 26kDa enzyme tag.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab76440 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
WB
  • 追加情報ELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 1 - 5 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 組織特異性Expressed in testis, ovary, liver, spleen, brain, kidney, prostate, lung, liver, and heart.
    • 関連疾患Defects in TSPYL1 are the cause of sudden infant death with dysgenesis of the testes syndrome (SIDDT) [MIM:608800]. SIDDT is an autosomal recessive disorder. Affected infants appear normal at birth, develop signs of visceroautonomic dysfunction early in life, and die before 12 months of age of abrupt cardiorespiratory arrest. Features included bradycardia, hypothermia, severe gastroesophageal reflux, laryngospasm, bronchospasm, and abnormal cardiorespiratory patterns during sleep. Genotypic males with SIDDT had fetal testicular dysgenesis and ambiguous genitalia, with findings such as intraabdominal testes, dysplastic testes, deficient fetal testosterone production, fusion and rugation of the gonadal sac, and partial development of the penile shaft. Female sexual development was normal. Affected infants had an unusual staccato cry, similar to the cry of a goat.
    • 配列類似性Belongs to the nucleosome assembly protein (NAP) family.
    • 細胞内局在Nucleus > nucleolus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • SIDDT antibody
      • Testis specific like protein Y encoded antibody
      • Testis specific Y encoded like protein 1 antibody
      • Testis-specific Y-encoded-like protein 1 antibody
      • TSPY like antibody
      • TSPY like 1 antibody
      • TSPY like protein 1 antibody
      • TSPY-like protein 1 antibody
      • TSPYL antibody
      • TSPYL1 antibody
      • TSYL1_HUMAN antibody
      see all

    Anti-TSPYL1 antibody 画像

    • Anti-TSPYL1 antibody (ab76440) at 5 µg/ml + immunogen at 0.1 µg

      Secondary
      Goat anti-mouse IgG (H&L)-HRP conjugate at 1/5000 dilution

      Predicted band size : 37 kDa
      Observed band size : 37 kDa

    Anti-TSPYL1 antibody (ab76440) 使用論文

    ab76440 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab76440.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"