製品の概要

  • 製品名Anti-TSPAN12 antibody
    TSPAN12 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TSPAN12
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    KLH conjugated synthetic peptide selected from the C-terminal region of Human TSPAN12 (NP_036470.1).

  • ポジティブ・コントロール
    • T47D cell line lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab93179 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報ELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 35 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性TSPAN12 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. It is a regulator of cell surface receptor signal transduction and plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction. It acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs. It also acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP. It activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP) and activates MMP14/MT1-MMP-dependent cleavage activity.
    • 細胞内局在Cell membrane; Multi-pass membrane protein.
    • 参照データベース
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    Anti-TSPAN12 antibody 画像

    • Anti-TSPAN12 antibody (ab93179) at 1/100 dilution + T47D cell line lysate at 35 µg

      Predicted band size : 35 kDa

    Anti-TSPAN12 antibody (ab93179) 使用論文

    ab93179 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab93179.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"