製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to TRPV5
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Cow, Dog, Pig
  • 免疫原

    Synthetic peptide:

    C-SHRGWEILRQNT

    , corresponding to amino acids 697-708 of Human TRPV5 (NP_062815.2).

  • ポジティブ・コントロール
    • Human Pancreas lysate.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab77351 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報
    Peptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution: 1/16000.
    WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 85 kDa (predicted molecular weight: 83 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.
    • 組織特異性
      Expressed at high levels in kidney, small intestine and pancreas, and at lower levels in testis, prostate, placenta, brain, colon and rectum.
    • 配列類似性
      Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV5 sub-subfamily.
      Contains 5 ANK repeats.
    • 翻訳後修飾
      Glycosylated.
    • 細胞内局在
      Apical cell membrane. Colocalized with S100A10 and ANAX2 along the apical domain of kidney distal tubular cells (By similarity). The expression of the glycosylated form in the cell membrane is increased in the presence of WNK3.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Calcium transport protein 2 antibody
      • Calcium transporter 2 antibody
      • CAT 2 antibody
      • CAT2 antibody
      • ECAC 1 antibody
      • ECaC antibody
      • ECaC1 antibody
      • Epithelial calcium channel 1 antibody
      • Osm 9 like TRP channel 3 antibody
      • Osm-9-like TRP channel 3 antibody
      • OTRPC 3 antibody
      • OTRPC3 antibody
      • Transient receptor potential cation channel subfamily V member 5 antibody
      • TRPV 5 antibody
      • TrpV5 antibody
      • TRPV5_HUMAN antibody
      see all

    Anti-TRPV5 antibody 画像

    • Anti-TRPV5 antibody (ab77351) at 1 µg/ml + Human pancreas lysate in RIPA buffer at 35 µg

      Predicted band size : 83 kDa
      Observed band size : 83 kDa

    プロトコール

    Anti-TRPV5 antibody (ab77351) 使用論文

    ab77351 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab77351.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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