製品の概要

  • 製品名
    Anti-TRPM6 antibody
  • 製品の詳細
    Guinea pig polyclonal to TRPM6
  • アプリケーション
    適用あり: IHC-Frmore details
  • 種交差性
    交差種: Rat
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide:

    GCERDKNRSSLERHTRL

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab47017 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-Fr 1/100 - 1/1000.

ターゲット情報

  • 関連性
    TRPM6 is an essential ion channel and serine/threonine-protein kinase, and is crucial for magnesium homeostasis. TRPM6 also has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. The various isoforms of the type M6-kinase lack the ion channel region.
  • 細胞内局在
    Multi-pass membrane protein.
  • 参照データベース
  • 別名
    • CHAK2 antibody
    • Channel kinase 2 antibody
    • HMGX antibody
    • HOMG antibody
    • HSH antibody
    • Melastatin related TRP cation channel 6 antibody
    • Transient receptor potential cation channel subfamily M member 6 antibody
    see all

画像

  • Immunohistochemical staining of frozen rat kidney tissue, using ab47017. Secondary staining was carried out using a Cy3 conjugated antibody.

プロトコール

参考文献

This product has been referenced in:
  • Boyden LM  et al. Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities. Nature 482:98-102 (2012). Read more (PubMed: 22266938) »
  • Sipos F  et al. Peripheral blood based discrimination of ulcerative colitis and Crohn's disease from non-IBD colitis by genome-wide gene expression profiling. Dis Markers 30:1-17 (2011). Read more (PubMed: 21508504) »

See all 2 Publications for this product

レビューと Q&A

Thank you for your reply and your patience with this response.

I heard back from the lab in Australia, and unfortunately none of our anti-TRPM6 antibodies (ab47017, ab62990, ab63089, ab72153, ab74850, ab77499, ab79227) show significant homolo...

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Thank you for your inquiry.

I just wanted to give you an update.

We have 7 anti-TRPM6 antibodies in the catalogue. We wouldn't expect ab47017 to work in bovine, because the immunogen sequence really does not show any homology with b...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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