製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to TRPC1
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Dog
  • 免疫原

    Synthetic peptide to an internal region of Human TRPC1 conjugated to KLH.

  • ポジティブ・コントロール
    • Human cortex, Human Prostate (fibromuscular stroma)

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab110837 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能
    Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.
  • 組織特異性
    Seems to be ubiquitous.
  • 配列類似性
    Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
    Contains 4 ANK repeats.
  • 翻訳後修飾
    Activation of PRKCA induces phosphorylation of TRPC1 and subsequent Ca2+ entry into cells.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • HTRP 1 antibody
    • HTRP1 antibody
    • MGC133334 antibody
    • MGC133335 antibody
    • Mtrp1 antibody
    • Short transient receptor potential channel 1 antibody
    • Transient receptor potential canonical 1 antibody
    • Transient receptor potential cation channel subfamily C member 1 antibody
    • Transient receptor potential channel 1 antibody
    • Transient receptor protein 1 antibody
    • TRP 1 antibody
    • TRP 1 protein antibody
    • Trp related protein 1 antibody
    • TRP-1 antibody
    • TRP1 antibody
    • TRP1 protein antibody
    • TrpC1 antibody
    • Trpc1 transient receptor potential cation channel subfamily C member 1 antibody
    • TRPC1_HUMAN antibody
    • Trrp1 antibody
    see all

画像

  • ab110837 at 3.75 µg/ml staining TRPC1 in Human cortex by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.
  • ab110837 at 3.75 µg/ml staining TRPC1 in Human Prostate (fibromuscular stroma) by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.

プロトコール

参考文献

ab110837 has not yet been referenced specifically in any publications.

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