Use a concentration of 0.2 - 0.5 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).
May function as a growth factor receptor.
Placenta, pancreatic carcinoma cell lines.
Defects in TACSTD2 are the cause of gelatinous drop-like corneal dystrophy (GDLD) [MIM:204870]; also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment.
Belongs to the EPCAM family. Contains 1 thyroglobulin type-1 domain.