製品の概要

  • 製品名Anti-TrkC antibody
    TrkC 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to TrkC
  • 特異性This antibody is specific for rat TrkC at 145kDa and an additional band at approximately 100kDa.
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
    交差が予測される動物種: Chicken, Pig
  • 免疫原

    Recombinant entire extracellular domain of rat TrkC receptor, corresponding to aa1-429, expressed in COS cells.

  • ポジティブ・コントロール
    • Mouse brain membrane protein preparation.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab33656 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 145 kDa (predicted molecular weight: 68 kDa).

ターゲット情報

  • 機能Receptor for neurotrophin-3 (NT-3). This is a tyrosine-protein kinase receptor. Known substrates for the trk receptors are SHC1, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties.
  • 組織特異性Widely expressed but mainly in nervous tissue. Isoform B is expressed at higher levels in adult brain than in fetal brain.
  • 配列類似性Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 2 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 protein kinase domain.
  • 翻訳後修飾Ligand-mediated auto-phosphorylation.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • EC 2.7.10.1 antibody
    • ETS related protein neurotrophic receptor tyrosine kinase fusion antibody
    • ETS related protein neurotrophic receptor tyrosine kinase fusion protein antibody
    • ETV6 NTRK3 fusion antibody
    • GP145 TrkC antibody
    • gp145(trkC) antibody
    • GP145-TrkC antibody
    • GP145TrkC antibody
    • Neurotrophic tyrosine kinase receptor type 3 antibody
    • Neurotrophin 3 receptor antibody
    • NT 3 growth factor receptor antibody
    • NT 3 growth factor receptor precursor antibody
    • NT 3 receptor antibody
    • NT-3 growth factor receptor antibody
    • Ntrk3 antibody
    • NTRK3_HUMAN antibody
    • OTTHUMP00000192915 antibody
    • TRK C antibody
    • Trk-C antibody
    • TRKC antibody
    • TrkC tyrosine kinase antibody
    • Tyrosine kinase receptor C antibody
    see all

Anti-TrkC antibody (ab33656) 使用論文

ab33656 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. The immunogen for this product comprises the entire extracellular domain of rat TrkC receptor, corresponding to 1-429a.a, expressed in COS cells. Three isoforms of TrkC (isoforms A, B and C) differ in their amino aci...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"