製品の概要

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab123094 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 50 kDa.

ターゲット情報

  • 機能Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor.
  • 組織特異性Abundantly expressed in kidney, liver and lung. Lower levels in heart, placenta and pancreas. Expressed in colonic epithelial cells. Up-regulated in colonic tumors.
  • 配列類似性Belongs to the zyxin/ajuba family.
    Contains 3 LIM zinc-binding domains.
  • ドメインThe LIM zinc-binding domains mediate interaction with LPAR2 and with S.typhimurium protein sseI.
  • 翻訳後修飾Phosphorylation at Tyr-55 by SRC is required for enhancement of lysophosphatidic acid-induced cell migration. Tyr-55 is dephosphorylated by PTPN13.
  • 細胞内局在Cytoplasm > cytoskeleton. Cell junction > focal adhesion. Nucleus. Cytoplasm. Shuttles between nucleus and cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • MGC10556 antibody
    • MGC10558 antibody
    • MGC29959 antibody
    • MGC3837 antibody
    • MGC4423 antibody
    • OIP-1 antibody
    • OIP1 antibody
    • OPA interacting protein 1 antibody
    • OPA-interacting protein 1 antibody
    • Thyroid hormone receptor interactor 6 antibody
    • Thyroid receptor interacting protein 6 antibody
    • Thyroid receptor-interacting protein 6 antibody
    • TR-interacting protein 6 antibody
    • TRIP-6 antibody
    • Trip6 antibody
    • TRIP6_HUMAN antibody
    • TRIP6i2 antibody
    • ZRP 1 antibody
    • ZRP-1 antibody
    • Zyxin-related protein 1 antibody
    see all

Anti-TRIP6 antibody 画像

  • Anti-TRIP6 antibody (ab123094) at 1/100 dilution + HepG2 cell line lysates at 35 µg

    Predicted band size : 50 kDa

Anti-TRIP6 antibody (ab123094) 使用論文

ab123094 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab123094.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"