製品の概要

  • 製品名Anti-TRIM71 antibody
    TRIM71 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to TRIM71
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Rat, Cow, Dog, Human
  • 免疫原

    Synthetic peptide: C-NKLESTISAVQ, corresponding to internal sequence amino acids 409-419 of Human TRIM71 (NP_001034200.1).

  • ポジティブ・コントロール
    • NIH3T3 lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab99487 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノポリクローナル
  • アイソタイプIgG

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab99487 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 100 kDa (predicted molecular weight: 92 kDa). An approximately 100 kDa band was observed in lysates of the cell line NIH3T3. An additional band of unknown identity was also consistently observed at 14 kDa. This band was successfully blocked by incubation with the immunizing peptide.

ターゲット情報

  • 機能E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance. Binds to miRNAs and associates with AGO2, participating in post-transcriptional repression of transcripts such as CDKN1A. Facilitates the G1-S transition to promote rapid embryonic stem cell self-renewal by repressing CDKN1A expression. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development: positively regulates FGF signaling by controlling the stability of SHCBP1.
  • 組織特異性Specifically expressed in testis.
  • パスウェイProtein modification; protein ubiquitination.
  • 配列類似性Belongs to the TRIM/RBCC family.
    Contains 2 B box-type zinc fingers.
    Contains 1 filamin repeat.
    Contains 6 NHL repeats.
    Contains 1 RING-type zinc finger.
  • 翻訳後修飾Autoubiquitinated.
  • 細胞内局在Cytoplasm, P-body.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 2610206G21Rik antibody
    • Abnormal cell LINeage LIN 41 antibody
    • AL022943 antibody
    • E3 ubiquitin-protein ligase TRIM71 antibody
    • Gm1127 antibody
    • Homolog of C. elegans Lin 41 antibody
    • LIN 41 antibody
    • LIN41 antibody
    • LIN41_HUMAN antibody
    • mlin 41 antibody
    • Protein lin 41 homolog antibody
    • Protein lin-41 homolog antibody
    • RGD1566388 antibody
    • Ripply2 antibody
    • TRIM 71 antibody
    • TRIM71 antibody
    • Tripartite motif containing 71 antibody
    • Tripartite motif-containing protein 71 antibody
    see all

Anti-TRIM71 antibody 画像

  • Anti-TRIM71 antibody (ab99487) at 0.5 µg/ml + NIH3T3 lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 92 kDa

Anti-TRIM71 antibody (ab99487) 使用論文

ab99487 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab99487.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"