製品の概要

  • 製品名Anti-TRIM5 gamma antibody
    TRIM5 gamma 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TRIM5 gamma
  • アプリケーション適用あり: IHC-P, ICC/IF, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide (Human) (C terminal).

  • ポジティブ・コントロール
    • Human bladder and colon cell lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab17203 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 2 µg/ml.
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 35 kDa.

ターゲット情報

  • 機能Isoform Alpha is a retrovirus restriction factor, which mediates species-specific, early block to retrovirus infection. Targets retroviral capsid soon after entry into the cell, and prevents reverse transcription of the virus RNA genome. Isoform Alpha trimers may make multiple contacts with the hexameric lattice of CA proteins which constitute the surface of retrovirion core, and somehow inactivate the virus. Restricts efficiently infection by N-MLV, but not HIV-1. May have E3 ubiquitin-protein ligase activity.
  • パスウェイProtein modification; protein ubiquitination.
  • 配列類似性Belongs to the TRIM/RBCC family.
    Contains 1 B box-type zinc finger.
    Contains 1 B30.2/SPRY domain.
    Contains 1 RING-type zinc finger.
  • ドメインThe RING-type zinc finger domain mediates binding to an E2 ubiquitin-conjugating enzyme.
  • 翻訳後修飾Ubiquitinates itself in a RING finger- and UBE2D2-dependent manner (in vitro).
  • 細胞内局在Cytoplasm > P-body. Cytoplasmic bodies.
  • Information by UniProt
  • 参照データベース
  • 別名
    • RING finger protein 88 antibody
    • RNF88 antibody
    • TRIM5 antibody
    • TRIM5_HUMAN antibody
    • Tripartite motif containing 5 antibody
    • Tripartite motif protein TRIM5 antibody
    • Tripartite motif-containing protein 5 antibody
    see all

Anti-TRIM5 gamma antibody 画像

  • Immunofluorescence of TRIM5 gamma in Human bladder tissue with ab17203 at 20 ug/mL.

  • All lanes : Anti-TRIM5 gamma antibody (ab17203) at 2 µg/ml

    Lane 1 : Human bladder cell lysate
    Lane 2 : Human colon cell lysate


    Observed band size : 35 kDa (why is the actual band size different from the predicted?)
    Detection of TRIM5 gamma in human bladder (A) and colon (B) cell lysates. ab17203 used at 2 ug/ml. Band of ~35 kDa detected. 
  • ab17203 at 2µg/ml staining TRIM5 gamma in human bladder tissue by IHC

Anti-TRIM5 gamma antibody (ab17203) 使用論文

ab17203 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"