製品の概要

  • 製品名Anti-TRIM32 antibody
    TRIM32 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TRIM32
  • アプリケーション適用あり: WB, IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow
  • 免疫原

    Recombinant fragment, corresponding to a sequence within amino acids 1-259 of Human TRIM32 (AAH03154).

  • ポジティブ・コントロール
    • 293T and MOLT4 whole cell lysates; H441 Xenograft.

法規制情報

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab96612 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 72 kDa.
IHC-P 1/100 - 1/250.
ICC/IF 1/100 - 1/500.

ターゲット情報

  • 機能Has an E3 ubiquitin ligase activity. Ubiquitinates DTNBP1 (dysbindin) and promotes its degradation. May play a significant role in mediating the biological activity of the HIV-1 Tat protein in vivo. Binds specifically to the activation domain of HIV-1 Tat and can also interact with the HIV-2 and EIAV Tat proteins in vivo.
  • 組織特異性Spleen, thymus, prostate, testis, ovary, intestine, colon and skeletal muscle.
  • パスウェイProtein modification; protein ubiquitination.
  • 関連疾患Limb-girdle muscular dystrophy 2H (LGMD2H) [MIM:254110]: An autosomal recessive degenerative myopathy characterized by pelvic girdle, shoulder girdle and quadriceps muscle weakness. Clinical phenotype and severity are highly variable. Disease progression is slow and most patients remain ambulatory into the sixth decade of life. Note=The disease is caused by mutations affecting the gene represented in this entry.
    Bardet-Biedl syndrome 11 (BBS11) [MIM:209900]: A syndrome characterized by usually severe pigmentary retinopathy, early-onset obesity, polydactyly, hypogenitalism, renal malformation and mental retardation. Secondary features include diabetes mellitus, hypertension and congenital heart disease. Bardet-Biedl syndrome inheritance is autosomal recessive, but three mutated alleles (two at one locus, and a third at a second locus) may be required for clinical manifestation of some forms of the disease. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • 配列類似性Belongs to the TRIM/RBCC family.
    Contains 1 B box-type zinc finger.
    Contains 5 NHL repeats.
    Contains 1 RING-type zinc finger.
  • 翻訳後修飾Ubiquitinated.
  • 細胞内局在Cytoplasm. Localized in cytoplasmic bodies, often located around the nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 72 kda Tat interacting Protein antibody
    • 72 kDa Tat-interacting protein antibody
    • BBS11 antibody
    • E3 ubiquitin-protein ligase TRIM32 antibody
    • HT2A antibody
    • LGMD2H antibody
    • Limb girdle muscular dystrophy 2H (autosomal recessive) antibody
    • Limb girdle muscular dystrophy 2H antibody
    • Muscular dystrophy Hutterite type antibody
    • TAT interactive protein 72KD antibody
    • TATIP antibody
    • TRI32_HUMAN antibody
    • Trim32 antibody
    • Tripartite Motif Containing Protein 32 antibody
    • Tripartite motif-containing protein 32 antibody
    • Zinc finger protein HT2A antibody
    see all

Anti-TRIM32 antibody 画像

  • Anti-TRIM32 antibody (ab96612) at 1/1000 dilution + 293T whole cell lysate at 30 µg

    Predicted band size : 72 kDa
  • ab96612 at 1/100 dilution staining TRIM32 in H441 Xenograft by Immunohistochemistry, Paraffin-embedded tissue.
  • Immunofluorescence analysis of paraformaldehyde-fixed A431, using TRIM32(ab96612) antibody at 1:500 dilution.

Anti-TRIM32 antibody (ab96612) 使用論文

This product has been referenced in:
  • Crawford LJ  et al. Synergistic effects of proteasome inhibitor carfilzomib in combination with tyrosine kinase inhibitors in imatinib-sensitive and -resistant chronic myeloid leukemia models. Oncogenesis 3:e90 (2014). WB ; Human . Read more (PubMed: 24590311) »

See 1 Publication for this product

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Unfortunately we do not have any publications for this antibody yet. Also, we do not have any trial sized samples as we only have the sizes in stock that we sell (100ul).


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Thank you for contacting us.
You are correct, the WB image show TRIM32 72 KDA band in 293T cell lysates.
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