製品の概要

  • 製品名Anti-TRIM23 antibody
    TRIM23 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TRIM23
  • アプリケーション適用あり: WB, IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide containing a sequence corresponding to a region within amino acids 2-14 of Human TRIM23 (NP_150230).

  • ポジティブ・コントロール
    • WB: HeLaS3 whole cell lysate IHC-P: Gastric CA ICC/IF: HeLa cell

法規制情報

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.01% Thimerosal (merthiolate)
    Constituents: 20% Glycerol, 1% BSA, 1X PBS, pH 7.0
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab97291 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/300. Predicted molecular weight: 64 kDa.
IHC-P 1/100 - 1/500.
ICC/IF 1/100 - 1/200.

ターゲット情報

  • 機能Acts as an E3 ubiquitin-protein ligase. In the presence of the human cytomegalovirus (HCMV) protein UL144, participates in 'Lys-63'-linked auto-ubiquitination of TRAF6 resulting in the virally controlled activation of NF-kappa-B at early time of infection. The C-terminus can act as an allosteric activator of the cholera toxin catalytic subunit.
  • パスウェイProtein modification; protein ubiquitination.
  • 配列類似性In the C-terminal section; belongs to the small GTPase superfamily. Arf family.
    Contains 1 B box-type zinc finger.
    Contains 1 RING-type zinc finger.
  • ドメインThe RING-type zinc finger domain is responsible for E3 ubiquitin ligase activity.
  • 細胞内局在Endomembrane system. Golgi apparatus membrane. Lysosome membrane. Membrane-associated with the Golgi complex and lysosomal structures.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ADP ribosylation factor domain protein 1 antibody
    • ADP-ribosylation factor domain-containing protein 1 antibody
    • ARF domain protein 1 antibody
    • ARFD1 antibody
    • E3 ubiquitin-protein ligase TRIM23 antibody
    • GTP binding protein ARD 1 antibody
    • GTP-binding protein ARD-1 antibody
    • N-acetyltransferase ARD1 human homolog of antibody
    • N-acetyltransferase homolog of S. cerevisiae ARD1 antibody
    • RING finger protein 46 antibody
    • TRI23_HUMAN antibody
    • TRIM23 antibody
    • Tripartite motif protein TRIM23 antibody
    • Tripartite motif-containing protein 23 antibody
    see all

Anti-TRIM23 antibody 画像

  • Anti-TRIM23 antibody (ab97291) at 1/1000 dilution + HeLa S3 whole cell lysate at 30 µg

    Predicted band size : 64 kDa
  • Immunohistochemical analysis of TRIM23 in paraffin embedded gastric CA, using ab97291 at a 1/100 dilution.
  • Immunofluorescence analysis of TRIM23 in paraformaldehyde fixed HeLa, using ab97291 at a 1/200 dilution.
    Image 1: without co-staining; image 2: co-stained with Hoechst 33342.

Anti-TRIM23 antibody (ab97291) 使用論文

ab97291 has not yet been referenced specifically in any publications.

Product Wall

Ab97291 has been tested in WB with HeLa S3 (a clonal derivative of the HeLa line) and in ICC with HeLa cells. Both of these samples were endogenously expressing the target protein. The Human Protein Atlas also shows that HeLa cells have moderate abunda...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"