Trifluoperazine dihydrochloride (ab120739)

製品の概要

  • 製品名
    Trifluoperazine dihydrochloride
  • 製品の詳細
    Cell-permeable calmodulin antagonist
  • 生理活性の詳細
    Cell-permeable calmodulin antagonist. Dopamine receptor antagonist. Stimulates ER Ca2+ ATPase activity at low concentrations and inhibits at higher concentrations. Antipsychotic.
  • 精製度
    > 99%

製品の特性

参考文献

This product has been referenced in:
  • Feldkamp MD  et al. Allosteric effects of the antipsychotic drug trifluoperazine on the energetics of calcium binding by calmodulin. Proteins 78:2265-82 (2010). Read more (PubMed: 20544963) »
  • Khan SZ  et al. The effects of phenothiazines and other calmodulin antagonists on the sarcoplasmic and endoplasmic reticulum Ca(2+) pumps. Biochem Pharmacol 60:1797-806 (2000). Read more (PubMed: 11108794) »
  • Vandonselaar M  et al. Trifluoperazine-induced conformational change in Ca(2+)-calmodulin. Nat Struct Biol 1:795-801 (1994). Read more (PubMed: 7634090) »
  • Seeman P  et al. Antipsychotic drug doses and neuroleptic/dopamine receptors. Nature 261:717-9 (1976). Read more (PubMed: 945467) »

See 0 Publications for this product

レビューと Q&A


Thank you for your technical enquiry. After checking our records it
appears that there is an inaccuracy on the datasheet. I would like to
confirm that ab120739 is an antagonist of calmodulin.
I would like to apologize for this inacc...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

登録