製品の概要

  • 製品名Triciribine
  • 製品の詳細
    Selective, potent inhibitor of Akt activation
  • 別名
    • API 2
    • NSC 154020
    • TCN
  • 生理活性の詳細Cell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation and signalling of Akt. Selective over PKC, PKA, SGK and p38 pathways. Induces cell growth arrest and apoptosis in vitro.
  • 精製度> 98%

製品の特性

    Triciribine (ab120936) 使用論文

    This product has been referenced in:
    • Gloesenkamp CR  et al. AKT inhibition by triciribine alone or as combination therapy for growth control of gastroenteropancreatic neuroendocrine tumors. Int J Oncol 40:876-88 (2012). Read more (PubMed: 22075556) »
    • Yang L  et al. Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt. Cancer Res 64:4394-9 (2004). Read more (PubMed: 15231645) »
    • Wotring LL  et al. Dual mechanisms of inhibition of DNA synthesis by triciribine. Cancer Res 50:4891-9 (1990). Read more (PubMed: 2379153) »

    See 0 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab120936.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"