製品の概要

  • 製品名
    Triciribine
  • 製品の詳細
    Selective, potent inhibitor of Akt activation
  • 別名
    • API 2
    • NSC 154020
    • TCN
  • 生理活性の詳細
    Cell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation and signalling of Akt. Selective over PKC, PKA, SGK and p38 pathways. Induces cell growth arrest and apoptosis in vitro.
  • 精製度
    > 98%

製品の特性

参考文献

This product has been referenced in:
  • Gloesenkamp CR  et al. AKT inhibition by triciribine alone or as combination therapy for growth control of gastroenteropancreatic neuroendocrine tumors. Int J Oncol 40:876-88 (2012). Read more (PubMed: 22075556) »
  • Yang L  et al. Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt. Cancer Res 64:4394-9 (2004). Read more (PubMed: 15231645) »
  • Wotring LL  et al. Dual mechanisms of inhibition of DNA synthesis by triciribine. Cancer Res 50:4891-9 (1990). Read more (PubMed: 2379153) »

See 0 Publications for this product

レビューと Q&A

There are currently no Customer reviews or Questions for ab120936.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

登録