製品の概要

  • 製品名Anti-TREM1 antibody
    TREM1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to TREM1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Recombinant Fragment
    交差が予測される動物種: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 21-235 of Human TREM1

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG2b
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab57260 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock.
    • 組織特異性Highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. Also expressed in the lymph node, placenta, spinal cord and heart tissues. Expression is more elevated in peripheral blood leukocytes than in the bone marrow and in normal cells than malignant cells. Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. Strongly expressed in acute inflammatory lesions caused by bacteria and fungi. Isoform 2 was detected in the lung, liver and mature monocytes.
    • 配列類似性Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • 翻訳後修飾Glycosylated.
    • 細胞内局在Secreted and Cell membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CD354 antibody
      • OTTMUSP00000018206 antibody
      • TREM 1 antibody
      • TREM-1 antibody
      • TREM1 antibody
      • TREM1_HUMAN antibody
      • Triggering receptor expressed on monocytes 1 antibody
      • Triggering receptor expressed on myeloid cells 1 antibody
      • Triggering receptor TREM 1 antibody
      • Triggering receptor TREM1 antibody
      see all

    Anti-TREM1 antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab57260 TREM1 antibody at 1ug/ml. Detected band size is around 50 kDa.

    Anti-TREM1 antibody (ab57260) 使用論文

    ab57260 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab57260.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"