Anti-Treacher Collins syndrome protein 抗体 (ab57683)

製品の概要

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab57683 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能May be involved in nucleolar-cytoplasmic transport. May play a fundamental role in early embryonic development, particularly in development of the craniofacial complex.
    • 関連疾患Defects in TCOF1 are the cause of Treacher Collins syndrome type 1 (TCS1) [MIM:154500]. It is a form of Treacher Collins syndrome, a disorder of craniofacial development. Treacher Collins syndrome is characterized by a combination of bilateral downward slanting of the palpebral fissures, colobomas of the lower eyelids with a paucity of eyelashes medial to the defect, hypoplasia of the facial bones, cleft palate, malformation of the external ears, atresia of the external auditory canals, and bilateral conductive hearing loss.
    • 配列類似性Contains 1 LisH domain.
    • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 細胞内局在Nucleus > nucleolus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Mandibulofacial dysostosis antibody
      • MFD1 antibody
      • Nucleolar trafficking phosphoprotein antibody
      • TCOF 1 antibody
      • TCOF_HUMAN antibody
      • TCOF1 antibody
      • TCS antibody
      • TCS1 antibody
      • Treacher Collins Franceschetti syndrome 1 antibody
      • Treacher Collins syndrome antibody
      • Treacher Collins syndrome protein antibody
      • Treacle antibody
      • Treacle protein antibody
      see all

    Anti-Treacher Collins syndrome protein antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab57683 Treacher Collins syndrome protein antibody at 1ug/ml. Predicted band size of immunogen is 35 kDa

    Anti-Treacher Collins syndrome protein antibody (ab57683) 使用論文

    ab57683 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab57683.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"