製品の概要

  • 製品名Anti-TRAP220/MED1 antibody
    TRAP220/MED1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TRAP220/MED1
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Dog, Turkey, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between residues 1525 and the C-terminus (residue 1581) of human TRAP220/MED1 (NP_004765.2)

  • ポジティブ・コントロール
    • Human breast tumor and mouse squamous cell carcinoma tissues.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab84386 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報IHC-P: 1/100 - 1/500.
    Epitope exposure with citrate buffer will enhance staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    • 組織特異性Ubiquitously expressed.
    • 配列類似性Belongs to the Mediator complex subunit 1 family.
    • 翻訳後修飾Phosphorylated by MAPK1 or MAPK3 during G2/M phase which may enhance protein stability and promote entry into the nucleolus. Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 細胞内局在Nucleus. A subset of the protein may enter the nucleolus subsequent to phosphorylation by MAPK1 or MAPK3.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Activator-recruited cofactor 205 kDa component antibody
      • ARC205 antibody
      • CRSP1 antibody
      • CRSP200 antibody
      • DRIP205 antibody
      • DRIP230 antibody
      • MED1 antibody
      • MED1_HUMAN antibody
      • Mediator complex subunit 1 antibody
      • Mediator of RNA polymerase II transcription subunit 1 antibody
      • p53 regulatory protein RB18A antibody
      • PBP antibody
      • Peroxisome proliferator-activated receptor-binding protein antibody
      • PPAR binding protein antibody
      • PPAR-binding protein antibody
      • PPARBP antibody
      • PPARGBP antibody
      • RB18A antibody
      • Thyroid hormone receptor-associated protein complex 220 kDa component antibody
      • Thyroid receptor-interacting protein 2 antibody
      • TR-interacting protein 2 antibody
      • Trap220 antibody
      • TRIP-2 antibody
      • TRIP2 antibody
      • Vitamin D receptor-interacting protein complex component DRIP205 antibody
      see all

    Anti-TRAP220/MED1 antibody 画像

    • ab84386 at 1/250 dilution staining TRAP220/MED1 in human breast tumor by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.
    • ab84386 at 1/250 dilution staining TRAP220/MED1 in mouse squamous cell carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.

    Anti-TRAP220/MED1 antibody (ab84386) 使用論文

    ab84386 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab84386.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"