Anti-TGFBRAP1 抗体 (ab122468)
Key features and details
- Rabbit polyclonal to TGFBRAP1
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-TGFBRAP1 antibody
TGFBRAP1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to TGFBRAP1 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, WBmore details -
種交差性
交差種: Human -
免疫原
Recombinant fragment corresponding to Human TGFBRAP1 aa 712-807 (internal sequence).
Sequence:RQQLFHTLLAIYLHAGPTAHELAVAAVDLLNRHATEFDAAQVLQMLPDTW SVQLLCPFLMGAMRDSIHARRTMQVALGLARSENLIYTYDKMKLKG
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ポジティブ・コントロール
- Human pancreas tissue; RT 4 and U 251 MG cell lysates.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab122468の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
1/10 - 1/20. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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WB |
Use a concentration of 0.04 - 0.4 µg/ml.
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特記事項 |
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IHC-P
1/10 - 1/20. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
WB
Use a concentration of 0.04 - 0.4 µg/ml. |
ターゲット情報
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機能
Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2. -
配列類似性
Belongs to the TRAP1 family.
Contains 1 CNH domain. -
細胞内局在
Cytoplasm. Colocalizes with TGF-beta receptors in the absence of signaling. - Information by UniProt
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参照データベース
- Entrez Gene: 9392 Human
- Omim: 606237 Human
- SwissProt: Q8WUH2 Human
- Unigene: 446350 Human
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別名
- TGF-beta receptor-associated protein 1 antibody
- TGFA1_HUMAN antibody
- Tgfbrap1 antibody
see all
画像
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ab122468, at 1/10 dilution, staining TGFBRAP1 in paraffin-embedded Human pancreas tissue by Immunohistochemistry.
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All lanes : Anti-TGFBRAP1 antibody (ab122468) at 1/250 dilution
Lane 1 : RT 4 cell lysate
Lane 2 : U 251 MG cell lysate
Lane 3 : Human plasma lysate
Lane 4 : Human liver tissue lysate
Lane 5 : Human tonsil tissue lysate
Developed using the ECL technique.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab122468 は論文での使用が確認できていません。