製品の概要

  • 製品名Anti-Transglutaminase 5 antibody
    Transglutaminase 5 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Transglutaminase 5
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide: LGVLKPQHQA SIILETVPFK SGQRQIQANM RSNKFKDIKG YRNVYVDFAL , corresponding to C terminal amino acids 672-721 of Human Transglutaminase 5, (NP_963925).

  • ポジティブ・コントロール
    • HeLa cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab80907 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 37, 42, 80 kDa (predicted molecular weight: 80 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay 1/12500.

ターゲット情報

  • 機能Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes.
  • 組織特異性Expressed in foreskin keratinocytes.
  • 関連疾患Defects in TGM5 are a cause of peeling skin syndrome type A (APSS) [MIM:609796]. A non-inflammatory form of peeling skin syndrome, a genodermatosis characterized by the continuous shedding of the outer layers of the epidermis. In APSS patients, skin peeling is strictly limited to the dorsa of the hands and feet, and it is accompanied by accompanied by painless erythema and spontaneous non-scarring healing. Ultrastructural and histological analysis shows a level of blistering high in the epidermis at the stratum granulosum-stratum corneum junction.
  • 配列類似性Belongs to the transglutaminase superfamily. Transglutaminase family.
  • 細胞内局在Cytoplasm. Associated with intermediate filaments.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Protein glutamine gamma glutamyltransferase 5 antibody
    • Protein-glutamine gamma-glutamyltransferase 5 antibody
    • PSS2 antibody
    • TG(X) antibody
    • TGase 5 antibody
    • TGase X antibody
    • TGase-5 antibody
    • TGase5 antibody
    • TGASEX antibody
    • Tgm5 antibody
    • TGM5_HUMAN antibody
    • TGM6 antibody
    • TGMX antibody
    • TGX antibody
    • Transglutaminase X antibody
    • Transglutaminase-5 antibody
    see all

Anti-Transglutaminase 5 antibody 画像

  • Anti-Transglutaminase 5 antibody (ab80907) at 1 µg/ml + HeLa cell lysate

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 80 kDa
    Observed band size : 80 kDa
    Additional bands at : 37 kDa,42 kDa. We are unsure as to the identity of these extra bands.

Anti-Transglutaminase 5 antibody (ab80907) 使用論文

ab80907 has not yet been referenced specifically in any publications.

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