Anti-Transferrin Receptor 抗体 [MEM-75] (Phycoerythrin) (ab18242)


  • 製品名Anti-Transferrin Receptor antibody [MEM-75] (Phycoerythrin)
    Transferrin Receptor 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [MEM-75] to Transferrin Receptor (Phycoerythrin)
  • 標識Phycoerythrin. Ex: 488nm, Em: 575nm
  • 特異性CD71 antigen (transferrin receptor). This antibody does not block binding of transferrin to the receptor.
  • アプリケーション適用あり: Flow Cytmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Pre-B cell line NALM-6 (Human).

  • ポジティブ・コントロール
    • Human blood cells.



Our Abpromise guarantee covers the use of ab18242 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 10µl for 10100000 cells. or 10 ul per 100 ul of whole blood.

ab91357-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.


  • 機能Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. Positively regulates T and B cell proliferation through iron uptake (PubMed:26642240).
    (Microbial infection) Acts as a receptor for new-world arenaviruses: Guanarito, Junin and Machupo virus.
  • 関連疾患Immunodeficiency 46
  • 配列類似性Belongs to the peptidase M28 family. M28B subfamily.
    Contains 1 PA (protease associated) domain.
  • 翻訳後修飾N- and O-glycosylated, phosphorylated and palmitoylated. The serum form is only glycosylated.
    Proteolytically cleaved on Arg-100 to produce the soluble serum form (sTfR).
    Palmitoylated on both Cys-62 and Cys-67. Cys-62 seems to be the major site of palmitoylation.
  • 細胞内局在Secreted and Cell membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD 71 antibody
    • CD71 antibody
    • CD71 antigen antibody
    • OTTHUMP00000208523 antibody
    • OTTHUMP00000208524 antibody
    • OTTHUMP00000208525 antibody
    • p90 antibody
    • sTfR antibody
    • T9 antibody
    • TFR 1 antibody
    • TfR antibody
    • TfR1 antibody
    • TFR1_HUMAN antibody
    • TFRC antibody
    • TR antibody
    • Transferrin receptor (p90 CD71) antibody
    • Transferrin receptor protein 1, serum form antibody
    • Trfr antibody
    see all

Anti-Transferrin Receptor antibody [MEM-75] (Phycoerythrin) (ab18242) 使用論文

ab18242 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us. The content of vial is 1000 ul solution, at 10 ul per 100 ul of blood or with 1 million cells it will be suitable for 100 tests. Currently the datasheet show 20 ul per 100 ul; I have corrected the error which...

Read More