製品の概要

  • 製品名
    Anti-TRAF5 antibody [55A219]
    TRAF5 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [55A219] to TRAF5
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Fusion protein corresponding to Human TRAF5 aa 77-186 (internal sequence).
    Sequence:

    TVPICPVDKEVIKSQEVFKDNCCKREVLNLYVYCSNAPGCNAKVILGRYQ DHLQQCLFQPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVV VINLQNHEEN

  • ポジティブ・コントロール
    • Human kidney tissue

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファー
    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度
    Protein G purified
  • ポリ/モノ
    モノクローナル
  • クローン名
    55A219
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab115589 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 2 µg/ml. Predicted molecular weight: 64 kDa.
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能
    Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis.
  • 組織特異性
    Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and peripheral blood.
  • 配列類似性
    Belongs to the TNF receptor-associated factor family. A subfamily.
    Contains 1 MATH domain.
    Contains 1 RING-type zinc finger.
    Contains 2 TRAF-type zinc fingers.
  • ドメイン
    The MATH/TRAF domain binds to receptor cytoplasmic domains.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • MGC:39780 antibody
    • RING finger protein 84 antibody
    • RNF 84 antibody
    • RNF84 antibody
    • TNF receptor associated factor 5 antibody
    • TNF receptor-associated factor 5 antibody
    • TRAF 5 antibody
    • Traf5 antibody
    • TRAF5_HUMAN antibody
    see all

画像

  • ab115589, at 10 µg/ml, staining TRAF5 in formalin fixed, paraffin embedded Human kidney tissue by Immunohistochemistry. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

参考文献

This product has been referenced in:
  • Siriboon C  et al. Putative porcine embryonic stem cell lines derived from aggregated four-celled cloned embryos produced by oocyte bisection cloning. PLoS One 10:e0118165 (2015). Read more (PubMed: 25680105) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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