製品の概要

  • 製品名Anti-TRAF4 antibody
    TRAF4 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to TRAF4
  • アプリケーション適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length human TRAF4 protein (NP_004286.2).

  • ポジティブ・コントロール
    • WB: human pancreas tissue lysate, TRAF4 transfected 293T cell lysate ICC/IF: HeLa cell

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab88612 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 54 kDa.
ICC/IF Use a concentration of 10 µg/ml.

ターゲット情報

  • 機能Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract (By similarity). Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions.
  • 組織特異性Expressed in epithelial cells of thymus, dendritic cells of lymph node, and in the basal cell layer of epithelia such as epidermis, nasopharynx, respiratory tract, salivary gland, and esophagus.
  • 配列類似性Belongs to the TNF receptor-associated factor family. B subfamily.
    Contains 1 MATH domain.
    Contains 1 RING-type zinc finger.
    Contains 3 TRAF-type zinc fingers.
  • ドメインThe coiled coil domain mediates homo- and hetero-oligomerization.
    The MATH/TRAF domain binds to receptor cytoplasmic domains.
  • 翻訳後修飾Polyubiquitinated, leading to its proteasomal degradation.
  • 細胞内局在Cytoplasm. Nucleus. Cytoplasm > perinuclear region. Cell junction > tight junction. Cell membrane. Cytoplasm > cytoskeleton.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CART 1 antibody
    • CART1 antibody
    • cysteine rich domain associated with ring and TRAF domain antibody
    • Cysteine rich domain associated with RING and Traf domains protein 1 antibody
    • Cysteine-rich domain associated with RING and Traf domains protein 1 antibody
    • Malignant 62 antibody
    • Metastatic lymph node gene 62 protein antibody
    • MLN 62 antibody
    • MLN62 antibody
    • RING finger protein 83 antibody
    • RNF 83 antibody
    • RNF83 antibody
    • TNF receptor associated factor 4 antibody
    • TNF receptor-associated factor 4 antibody
    • TRAF 4 antibody
    • Traf4 antibody
    • TRAF4_HUMAN antibody
    • tumor necrosis receptor-associated factor 4A antibody
    see all

Anti-TRAF4 antibody 画像

  • Anti-TRAF4 antibody (ab88612) at 1 µg/ml + human pancreas tissue lysate at 50 µg

    Predicted band size : 54 kDa
    Observed band size : 45 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-TRAF4 antibody (ab88612) at 1 µg/ml

    Lane 1 : TRAF4 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 54 kDa
    Observed band size : 54 kDa
  • ab88612, at 10 µg/ml, staining TRAF4 on HeLa cell by Immunofluorescence.

Anti-TRAF4 antibody (ab88612) 使用論文

ab88612 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab88612.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"