製品の概要

  • 製品名Anti-TRAF4 antibody
    TRAF4 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to TRAF4
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region between C terminal amino acids 426-455 of Human TRAF4 (NP_004286.2).

  • ポジティブ・コントロール
    • HepG2 cell line lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab124246 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 54 kDa.

ターゲット情報

  • 機能Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract (By similarity). Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions.
  • 組織特異性Expressed in epithelial cells of thymus, dendritic cells of lymph node, and in the basal cell layer of epithelia such as epidermis, nasopharynx, respiratory tract, salivary gland, and esophagus.
  • 配列類似性Belongs to the TNF receptor-associated factor family. B subfamily.
    Contains 1 MATH domain.
    Contains 1 RING-type zinc finger.
    Contains 3 TRAF-type zinc fingers.
  • ドメインThe coiled coil domain mediates homo- and hetero-oligomerization.
    The MATH/TRAF domain binds to receptor cytoplasmic domains.
  • 翻訳後修飾Polyubiquitinated, leading to its proteasomal degradation.
  • 細胞内局在Cytoplasm. Nucleus. Cytoplasm > perinuclear region. Cell junction > tight junction. Cell membrane. Cytoplasm > cytoskeleton.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CART 1 antibody
    • CART1 antibody
    • cysteine rich domain associated with ring and TRAF domain antibody
    • Cysteine rich domain associated with RING and Traf domains protein 1 antibody
    • Cysteine-rich domain associated with RING and Traf domains protein 1 antibody
    • Malignant 62 antibody
    • Metastatic lymph node gene 62 protein antibody
    • MLN 62 antibody
    • MLN62 antibody
    • RING finger protein 83 antibody
    • RNF 83 antibody
    • RNF83 antibody
    • TNF receptor associated factor 4 antibody
    • TNF receptor-associated factor 4 antibody
    • TRAF 4 antibody
    • Traf4 antibody
    • TRAF4_HUMAN antibody
    • tumor necrosis receptor-associated factor 4A antibody
    see all

Anti-TRAF4 antibody 画像

  • Anti-TRAF4 antibody (ab124246) at 1/100 dilution + HepG2 cell line lysates at 35 µg

    Predicted band size : 54 kDa

Anti-TRAF4 antibody (ab124246) 使用論文

ab124246 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab124246.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"