製品の概要

  • 製品名Anti-TPOR antibody
    TPOR 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to TPOR
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length TPOR protein (Human) (NP_005364)

  • ポジティブ・コントロール
    • TPOR transfected 293T cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab70194 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 71 kDa.

ターゲット情報

  • 機能Receptor for thrombopoietin. May represent a regulatory molecule specific for TPO-R-dependent immune responses.
  • 組織特異性Expressed at a low level in a large number of cells of hematopoietic origin. Isoform 1 and isoform 2 are always found to be coexpressed.
  • 関連疾患Defects in MPL are a cause of congenital amegakaryocytic thrombocytopenia (CAMT) [MIM:604498]. CAMT is a disease characterized by isolated thrombocytopenia and megakaryocytopenia with no physical anomalies.
  • 配列類似性Belongs to the type I cytokine receptor family. Type 1 subfamily.
    Contains 2 fibronectin type-III domains.
  • ドメインThe WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is required for JAK interaction and/or activation.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C MPL antibody
    • CD110 antibody
    • mpl antibody
    • MPLV antibody
    • Myeloproliferative leukemia protein antibody
    • Myeloproliferative leukemia virus oncogene antibody
    • Proto-oncogene c-Mpl antibody
    • THCYT2 antibody
    • Thrombopoietin receptor antibody
    • TPO R antibody
    • TPO-R antibody
    • TPOR antibody
    • TPOR_HUMAN antibody
    see all

Anti-TPOR antibody (ab70194) 使用論文

ab70194 has not yet been referenced specifically in any publications.

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